| Gene Symbol |
EZR/MSN/RDX
|
| Gene Synonyms |
CVL CVIL VIL2 HEL-S-105/HEL70 IMD50/DFNB24 |
| Gene Full Name |
ezrin/moesin/radixin |
| Gene Summary |
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008] |
| Alternative Names |
Villin 2 ezrin CVIL CVL Cytovillin 2 Cytovillin DKFZp762H157 Epididymis secretory protein Li 105 EZR EZRI_HUMAN Ezrin FLJ26216 HEL S 105 MGC1584 p81 VIL 2 VIL2 Villin 2 (ezrin) Villin 2 Villin-2 Villin2 Epididymis luminal protein 70 HEL70 Membrane organizing extension spike protein Membrane-organizing extension spike protein MOES_HUMAN Moesin Moesin/anaplastic lymphoma kinase fusion protein Msn MSN/ALK fusion CB567 CG12537 DFNB24 ESP10 Hh-induced MATH and BTB domain-containing protein HIB Moesin-B Protein roadkill RADI_HUMAN Radixin RDX
|
| Molecular Weight(MW) |
69 kDa,68 kDa,69 kDa |
| Cellular Localization |
Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane |