| Product Name | Anti-Phospho-Gli2 (Ser149) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser149 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GLI2 |
|---|---|
| Gene Synonyms | CJS HPE9 PHS2 THP1 THP2 |
| Gene Full Name | GLI family zinc finger 2 |
| Gene Summary | This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008] |
| Alternative Names | CJS Gli 2 GLI family zinc finger 2 GLI Kruppel family member GLI2 GLI2 GLI2_HUMAN Glioma associated oncogene family zinc finger HPE9 Oncogene GLI2 PHS2 Tax helper protein 1 Tax helper protein 2 Tax helper protein Tax responsive element 2 holding protein Tax responsive element 25 bp sequence binding protein THP THP1 THP2 Zinc finger protein GLI2 |
| Molecular Weight(MW) | 168 kDa |
| Cellular Localization | Cell projection, Cilium, Cytoplasm, Nucleus |
| SwissProt ID | P10070 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
