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OM683984
Discount Price
OM683984-100ul
100ul
Product Profile
Product Name Anti-Phospho-Gli2 (Ser234) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Ser234
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol GLI2
Gene Synonyms CJS
HPE9
PHS2
THP1
THP2
Gene Full Name GLI family zinc finger 2
Gene Summary This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008]
Alternative Names CJS
Gli 2
GLI family zinc finger 2
GLI Kruppel family member GLI2
GLI2
GLI2_HUMAN
Glioma associated oncogene family zinc finger
HPE9
Oncogene GLI2
PHS2
Tax helper protein 1
Tax helper protein 2
Tax helper protein
Tax responsive element 2 holding protein
Tax responsive element 25 bp sequence binding protein
THP
THP1
THP2
Zinc finger protein GLI2
Molecular Weight(MW) 168 kDa
Cellular Localization Cell projection,Cilium,Cytoplasm,Nucleus.
Database Links
SwissProt ID P10070
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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