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OM682868
Discount Price
OM682868-100ul
100ul
Product Profile
Product Name Anti-Phospho-Caspase 9 (Ser196) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH
Modification p-Ser196
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CASP9
Gene Synonyms MCH6
APAF3
APAF-3
PPP1R56
ICE-LAP6
Gene Full Name caspase 9
Gene Summary This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Alternative Names APAF-3
APAF3
Apoptosis related cysteine peptidase
Apoptotic protease Mch-6
Apoptotic protease-activating factor 3
CASP-9
CASP9
CASP9_HUMAN
Caspase 9 apoptosis related cysteine peptidase
Caspase 9 Dominant Negative
Caspase 9c
Caspase-9
Caspase-9 subunit p10
ICE LAP6
ICE like apoptotic protease 6
ICE-LAP6
ICE-like apoptotic protease 6
MCH6
PPP1R56
protein phosphatase 1
regulatory subunit 56
RNCASP9
Molecular Weight(MW) 46 kDa
Database Links
SwissProt ID P55211
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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