| Product Name | Anti-Phospho-TGFBR2 (Ser225/Ser250) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser225/Ser250 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TGFBR2 |
|---|---|
| Gene Synonyms | AAT3 FAA3 LDS2 MFS2 RIIC LDS1B LDS2B TAAD2 TBRII TBR-ii TGFR-2 tbetaR-II TGFbeta-RII |
| Gene Full Name | transforming growth factor beta receptor 2 |
| Gene Summary | The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Aug 2017] |
| Alternative Names | AAT3 FAA3 LDS1B LDS2 LDS2B MFS2 RIIC TAAD2 TbetaR II TbetaR-II TGF beta receptor type 2 TGF beta receptor type II TGF beta receptor type IIB TGF beta type II receptor TGF-beta receptor type II TGF-beta receptor type-2 TGF-beta type II receptor TGF-beta-R2 TGFB R2 TGFbeta - RII TGFbeta RII Tgfbr2 TGFR-2 TGFR2_HUMAN Transforming growth factor beta receptor II Transforming growth factor beta receptor type II Transforming growth factor beta receptor type IIC Transforming growth factor beta receptor II (70/80kDa) transforming growth factor beta receptor II alpha transforming growth factor beta receptor II beta transforming growth factor beta receptor II delta transforming growth factor beta receptor II epsilon transforming growth factor beta receptor II gamma Transforming growth factor-beta receptor type II |
| Molecular Weight(MW) | 65 kDa |
| Cellular Localization | Cell membrane,Membrane,Secreted. |
| SwissProt ID | P37173 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
