| Gene Symbol |
PABPC1
|
| Gene Synonyms |
PAB1 PABP PABP1 PABPC2 PABPL1 |
| Gene Full Name |
poly(A) binding protein cytoplasmic 1 |
| Gene Summary |
This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010] |
| Alternative Names |
PAB 1 PAB1 PABP 1 PABP1 PABPC 1 PABPC1 PABPC2 PABPL1 Poly A binding protein 1 Poly A binding protein cytoplasmic 1 poly(A) binding protein cytoplasmic 1 poly(A) binding protein cytoplasmic 2 Polyadenylate binding protein 1 |
| Molecular Weight(MW) |
71 kDa |
| Cellular Localization |
Cell projection,Cytoplasm,Nucleus,Spliceosome. |