| Gene Symbol |
ZEB2
|
| Gene Synonyms |
SIP1 SIP-1 ZFHX1B HSPC082 SMADIP1 |
| Gene Full Name |
zinc finger E-box binding homeobox 2 |
| Gene Summary |
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010] |
| Alternative Names |
FLJ42816 HSPC082 KIAA0569 SIP 1 SIP1 Smad Interacting Protein 1 Smad-interacting protein 1 SMADIP 1 SMADIP1 ZEB 2 Zeb2 ZEB2_HUMAN Zfhx1b ZFHX1B protein Zfx1b Zinc finger E box binding protein 2 Zinc finger E-box-binding homeobox 2 Zinc finger homeobox 1b zinc finger homeobox protein 1 Zinc finger homeobox protein 1b |
| Molecular Weight(MW) |
136 kDa |
| Cellular Localization |
Chromosome, Nucleus. |