| Product Name | Anti-Phospho-AIRE (Ser156) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser156 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | AIRE |
|---|---|
| Gene Synonyms | APS1 APSI PGA1 AIRE1 APECED |
| Gene Full Name | autoimmune regulator |
| Gene Summary | This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012] |
| Alternative Names | AIRE AIRE_HUMAN AIRE1 APECED APECED protein APS1 APSI Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein Autoimmune regulator Autoimmune regulator protein PGA1 |
| Molecular Weight(MW) | 58 kDa |
| Cellular Localization | Cytoplasm, Nucleus. |
| SwissProt ID | O43918 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
