| Product Name | Anti-Phospho-IGF2R (Ser2409) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser2409 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | IGF2R |
|---|---|
| Gene Synonyms | MPR1 MPRI CD222 CIMPR M6P-R MPR300 CI-M6PR MPR 300 M6P/IGF2R |
| Gene Full Name | insulin like growth factor 2 receptor |
| Gene Summary | This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015] |
| Alternative Names | 300 kDa mannose 6 phosphate receptor 300 kDa mannose 6-phosphate receptor Cation independent mannose 6 phosphate receptor Cation-independent mannose-6-phosphate receptor CD222 CD222 antigen CI Man 6 P receptor CI Man-6-P receptor CI MPR CI-M6PR CI-MPR CIMPR IGF 2 receptor IGF 2R IGF II receptor IGF-II receptor IGF2 receptor Igf2r Insulin like growth factor 2 receptor Insulin like growth factor II receptor Insulin-like growth factor 2 receptor Insulin-like growth factor II receptor M6P R M6P/IGF2 receptor M6P/IGF2R M6PR mannose 6 phosphate receptor mannose 6 phosphate receptor cation independent MPR 300 MPR300 MPRI MPRI_HUMAN |
| Molecular Weight(MW) | 274 kDa |
| Cellular Localization | Endosome, Golgi apparatus, Membrane. |
| SwissProt ID | P11717 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
