| Product Name | Anti-Phospho-SOS1 (Ser1082) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser1082 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SOS1 |
|---|---|
| Gene Synonyms | GF1 HGF NS4 GGF1 GINGF SOS-1 |
| Gene Full Name | SOS Ras/Rac guanine nucleotide exchange factor 1 |
| Gene Summary | This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008] |
| Alternative Names | alternate SOS1 GF1 GGF1 GINGF gingival fibromatosis gingival fibromatosis hereditary 1 Guanine nucleotide exchange factor HGF NS4 Son of sevenless homolog 1 (Drosophila) Son of sevenless homolog 1 SOS Ras/Rac guanine nucleotide exchange factor 1 SOS-1 Sos1 SOS1_HUMAN |
| Molecular Weight(MW) | 152 kDa |
| Cellular Localization | cytoplasm, cytosol, glutamatergic synapse, GTPase complex, neuronal cell body, plasma membrane, postsynaptic density. |
| SwissProt ID | Q07889 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
