| Gene Symbol |
MYH9
|
| Gene Synonyms |
MHA FTNS EPSTS BDPLT6 DFNA17 MATINS NMMHCA NMHC-II-A NMMHC-IIA |
| Gene Full Name |
myosin heavy chain 9 |
| Gene Summary |
This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011] |
| Alternative Names |
BDPLT 6 BDPLT6 Cellular myosin heavy chain Cellular myosin heavy chain type A DFNA 17 DFNA17 EPSTS FTNS MGC104539 MHA MYH 2A MYH 9 MYH2A MYH9 MYH9_HUMAN MYHas8 MyHC 2A MyHC IIa MyHC2A MyHCIIa MYHSA 2 MYHSA2 Myosin 9 Myosin heavy chain 9 Myosin heavy chain 9 non muscle Myosin heavy chain Myosin heavy chain non muscle IIa Myosin heavy chain nonmuscle IIa Myosin heavy polypeptide 2 Myosin heavy polypeptide 9 non muscle Myosin-9 Myosin9 NMHC II A NMMHC A NMMHC II a NMMHC II-a NMMHC IIA NMMHC-A NMMHC-IIA NMMHCA Non muscle myosin heavy chain A Non muscle myosin heavy chain Non muscle myosin heavy chain II A Non muscle myosin heavy polypeptide 9 non-muscle IIa Non-muscle myosin heavy chain A Non-muscle myosin heavy chain IIa Nonmuscle myosin heavy chain A Nonmuscle myosin heavy chain II A type A |
| Molecular Weight(MW) |
227 kDa |
| Cellular Localization |
Cell membrane, Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Membrane. |