| Product Name | Anti-Phospho-ATR (Thr1989) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Thr1989 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ATR |
|---|---|
| Gene Synonyms | FRP1 MEC1 SCKL FCTCS SCKL1 |
| Gene Full Name | ATR checkpoint kinase |
| Gene Summary | The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017] |
| Alternative Names | Ataxia telangiectasia and Rad3 related Ataxia telangiectasia and Rad3-related protein ATR ATR_HUMAN FCTCS FRAP Related Protein 1 FRAP-related protein 1 FRP1 MEC1 MEC1 mitosis entry checkpoint 1 homolog Protein kinase ATR RAC3 Rad3 related protein SCKL SCKL1 Serine/threonine protein kinase ATR Serine/threonine-protein kinase ATR |
| Molecular Weight(MW) | 301 kDa |
| Cellular Localization | Chromosome, Nucleus. |
| SwissProt ID | Q13535 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide |
