| Product Name | Anti-Phospho-VEGFR2 (Tyr1175) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Tyr1175 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | KDR |
|---|---|
| Gene Synonyms | FLK1 CD309 VEGFR VEGFR2 |
| Gene Full Name | kinase insert domain receptor |
| Gene Summary | Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009] |
| Alternative Names | CD309 CD309 antigen EC 2.7.10.1 Fetal liver kinase 1 FLK-1 FLK1 FLK1 mouse homolog of Kdr Kinase insert domain receptor (a type III receptor tyrosine kinase) Kinase insert domain receptor KRD1 Ly73 Protein tyrosine kinase receptor FLK1 Protein-tyrosine kinase receptor flk-1 soluble VEGFR2 Tyrosine kinase growth factor receptor Vascular endothelial growth factor receptor 2 VEGFR 2 VEGFR VEGFR-2 VEGFR2 VGFR2_HUMAN |
| Molecular Weight(MW) | 152 kDa |
| Cellular Localization | Cell junction, Cell membrane, Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Endosome, Membrane, Nucleus, Secreted. |
| SwissProt ID | P35968 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
