| Product Name | Anti-Phospho-PSMC5 (Ser120) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser120 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PSMC5 |
|---|---|
| Gene Synonyms | S8 p45 RPT6 SUG1 YKNS SUG-1 TBP10 TRIP1 p45/SUG |
| Gene Full Name | proteasome 26S subunit, ATPase 5 |
| Gene Summary | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] |
| Alternative Names | 26S protease regulatory subunit 8 26S proteasome AAA-ATPase subunit RPT6 Cim3 MSUG1 protein p45 p45/SUG Proteasome 26S ATPase subunit 5 Proteasome 26S subunit ATPase 5 Proteasome prosome macropain 26S subunit ATPase 5 Proteasome subunit p45 PRS8_HUMAN PSMC5 Rpt6 S8 SUG1 Tat binding protein homolog 10 TBP10 Thyroid hormone receptor interacting protein 1 Thyroid hormone receptor-interacting protein 1 Thyroid receptor interactor 1 TRIP1 TRIP1(SUG1) |
| Molecular Weight(MW) | 46 kDa |
| Cellular Localization | Cytoplasm, Nucleus, Proteasome. |
| SwissProt ID | P62195 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
