| Product Name | Anti-Phospho-SETD2 (Ser532) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser532 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SETD2 |
|---|---|
| Gene Synonyms | LLS HYPB SET2 HIF-1 HIP-1 KMT3A MRD70 RAPAS HBP231 HSPC069 p231HBP |
| Gene Full Name | SET domain containing 2, histone lysine methyltransferase |
| Gene Summary | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008] |
| Alternative Names | EC 2.1.1.43 FLJ16420 FLJ22472 FLJ23184 FLJ45883 HBP231 HIF 1 HIF-1 HIF1 HIP-1 Histone lysine N methyltransferase SETD2 Histone-lysine N-methyltransferase SETD2 hSET2 HSPC069 Huntingtin interacting protein 1 Huntingtin interacting protein Huntingtin interacting protein B Huntingtin interacting protein HYPB Huntingtin yeast partner B Huntingtin-binding protein 231-KD Huntingtin-interacting protein 1 Huntingtin-interacting protein B HYPB KIAA1732 KMT3A Lysine N methyltransferase 3A Lysine N-methyltransferase 3A p231HBP SET domain containing 2 SET domain-containing protein 2 SET2 SETD2 SETD2_HUMAN |
| Molecular Weight(MW) | 288 kDa |
| Cellular Localization | Chromosome,Nucleus. |
| SwissProt ID | Q9BYW2 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
