| Product Name | Anti-Phospho-Vinculin (Tyr692) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Tyr692 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | VCL |
|---|---|
| Gene Synonyms | MV MVCL VINC CMD1W CMH15 HEL114 |
| Gene Full Name | vinculin |
| Gene Summary | Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008] |
| Alternative Names | CMD1W CMH15 Epididymis luminal protein 114 HEL114 Metavinculin MV MVCL OTTHUMP00000019861 OTTHUMP00000019862 VCL VINC VINC_HUMAN Vinculin |
| Molecular Weight(MW) | 124 kDa |
| Cellular Localization | Cell junction,Cell membrane,Cell projection,Cytoplasm,Cytoskeleton,Membrane. |
| SwissProt ID | P18206 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
