| Product Name | Anti-Phospho-ATF4 (Ser219) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser219 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ATF4 |
|---|---|
| Gene Synonyms | CREB2 TXREB CREB-2 TAXREB67 |
| Gene Full Name | activating transcription factor 4 |
| Gene Summary | This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011] |
| Alternative Names | Activating transcription factor 4 ATF 4 ATF4 ATF4 protein ATF4_HUMAN cAMP-dependent transcription factor ATF-4 cAMP-responsive element-binding protein 2 CREB 2 CREB-2 CREB2 Cyclic AMP dependent transcription factor ATF 4 Cyclic AMP response element binding protein 2 Cyclic AMP-dependent transcription factor ATF-4 Cyclic AMP-responsive element-binding protein 2 DNA binding protein TAXREB67 DNA-binding protein TAXREB67 Tax Responsive Enhancer Element B67 Tax-responsive enhancer element-binding protein 67 TaxREB67 TXREB |
| Molecular Weight(MW) | 39 kDa |
| Cellular Localization | Cell membrane,Cytoplasm,Cytoskeleton,Membrane,Nucleus. |
| SwissProt ID | P18848 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
