| Gene Symbol |
YAP1
|
| Gene Synonyms |
YAP YKI COB1 YAP2 YAP-1 YAP65 |
| Gene Full Name |
Yes1 associated transcriptional regulator |
| Gene Summary |
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013] |
| Alternative Names |
65 kDa Yes associated protein 65 kDa Yes-associated protein COB1 YAp 1 YAP 65 YAP YAP-1 YAP1 YAP1_HUMAN YAP2 YAP65 yes -associated protein delta Yes associated protein 1 65kDa Yes associated protein 1 Yes associated protein 2 yes associated protein beta YKI Yorkie homolog |
| Molecular Weight(MW) |
54 kDa |
| Cellular Localization |
Cell junction, Cell membrane, Cytoplasm, Membrane, Nucleus, Tight junction. |