| Gene Symbol |
GRM5
|
| Gene Synonyms |
mGlu5 GPRC1E MGLUR5 PPP1R86 |
| Gene Full Name |
glutamate metabotropic receptor 5 |
| Gene Summary |
This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
| Alternative Names |
Glutamate receptor metabotropic 5 GPRC1E Grm5 GRM5_HUMAN Metabotropic glutamate receptor 5 Metabotropic glutamate receptor 5 variant F Metabotropic glutamate receptor 5 variant G Metabotropic glutamate receptor 5 variant H mGlu5 mGluR5 PPP1R86 Protein phosphatase 1 regulatory subunit 86 |
| Molecular Weight(MW) |
132 kDa |
| Cellular Localization |
Cell membrane. |