| Gene Symbol |
SMURF1
|
| Gene Full Name |
SMAD specific E3 ubiquitin protein ligase 1 |
| Gene Summary |
This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2010] |
| Alternative Names |
E3 ubiquitin-protein ligase SMURF1 hSMURF1 KIAA1625 Smad specific E3 ubiquitin ligase 1 SMAD specific E3 ubiquitin protein ligase 1 Smad ubiquitination regulatory factor 1 SMAD-specific E3 ubiquitin-protein ligase 1 SMUF1_HUMAN SMURF 1 smurf1 |
| Molecular Weight(MW) |
86 kDa |
| Cellular Localization |
Cell membrane, Cytoplasm, Membrane. |