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collagen II Goat pAb

Catalog Number:OM699572
Human;Mouse;Rat
WB;IF
OM699572
Discount Price
OM699572-100ul
100ul
Product Profile
Product Name collagen II Goat pAb
Antibody Type Primary Antibodies
Immunogen Recombinant Human collagen II
Modification Unmodified
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Goat
Tested Applications WBIF
WB:1:500-1:1000
IHC:1:100-1:500
IF-P:1:100-1:500
ICC/IF:1:100-1:300
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity Purified
Target Information
Gene Symbol COL2A1
Gene Synonyms AOM
ACG2
ANFH
LCPD
SEDC
STL1
VPED
ANFH1
EDMMD
OSCDP
PLSDT
SEDSTN
SMDALG
COL11A3
SEMDSTWK
Gene Full Name collagen type II alpha 1 chain
Gene Summary This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 142 kDa(Observed band size: 140 kDa)
Function COL2A1 is the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.
Cellular Localization Extracellular matrix,Secreted
Application

WB

Western blot analysis of Mouse testis and Rat testis lysates using collagen II Goat pAb

IF

Immunofluorescence analysis of Human testis cancer tissue using collagen II Goat pAb
Application Notes WB:1:500-1:1000
IHC:1:100-1:500
IF-P:1:100-1:500
ICC/IF:1:100-1:300
Additional Information
Form Liquid
Storage Instructions Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer Liquid in PBS, 50% glycerol, 0.05% Proclin 300, 0.08%BSA
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