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Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI)
Catalog Number:OM699702
Human
IHC;ICC/IF
OM699702
Discount Price
OM699702-100ul
100ul
Product Profile
Product Name Monoclonal Antibody to Cross Linked C-Telopeptide Of Type I Collagen (CTXI)
Antibody Type Primary Antibodies
Immunogen CPA665Mi31-KLH Conjugated Cross Linked C-Telopeptide Of Type I Collagen (CTXI)
Key Feature
Clonality Monoclonal
Isotype IgM Kappa
Host Species Mouse
Tested Applications IHCICC/IF
WB: 0.01-2µg/mL
IHC: 5-20µg/mL
ICC/IF: 5-20µg/mL
Species Reactivity Human
Concentration 1mg/ml
Purification Protein A/G
Target Information
Gene Symbol COL1A1
Gene Synonyms OI1,OI2,OI3,OI4,EDSC,CAFYD,EDSARTH1
Gene Full Name collagen type I alpha 1 chain
Gene Summary This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
Alternative Names CTX-I
CTX1
Application

IHC

DAB staining on IHC-P,Sample: Human Breast cancer Tissue,Primary Ab: 30µg/ml Mouse Anti-Multi-species CTXI Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody

IHC

DAB staining on IHC-P;Sample: Human Kidney Tissue;Primary Ab: 30µg/ml Mouse Anti-Multi-species CTXI AntibodySecond Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody

ICC/IF

AF488 staining on IF;Sample: U2OS cellPrimary Ab: 20µg/ml Mouse Anti-Multi-species CTXI AntibodySecond Ab: 2µg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
Application Notes WB: 0.01-2µg/mL
IHC: 5-20µg/mL
ICC/IF: 5-20µg/mL
Additional Information
Form Liquid
Storage Instructions Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Storage Buffer 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
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