| Product Name | Human PDGFA Recombinant protein |
|---|---|
| Species Reactivity | Human |
| Gene Symbol | PDGFA |
| Gene Synonyms | PDGF1 PDGF-A |
| Gene Full Name | platelet derived growth factor subunit A |
| Gene Summary | This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants. |
