Aldh1A1

Catalog Number：OM638959

  • Fig1: Western blot analysis of Aldh1A1 on 2 liver (1) and 2 kidney (2) tissue lysates using anti-Aldh1A1 antibody at 1/1,000 dilution.

  • Fig2: ICC staining Aldh1A1 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Fig3: ICC staining Aldh1A1 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Fig4: ICC staining Aldh1A1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Fig5: Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-Aldh1A1 antibody. Counter stained with hematoxylin.

  • Fig6: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Aldh1A1 antibody. Counter stained with hematoxylin.

  • Fig7: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Aldh1A1 antibody. Counter stained with hematoxylin.

  • Fig8: Immunohistochemical analysis of paraffin-embedded 2 colon tissue using anti-Aldh1A1 antibody. Counter stained with hematoxylin.

  • Fig9: Flow cytometric analysis of A549 cells with Aldh1A1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody;black).

  • Fig10: Flow cytometric analysis of HepG2 cells with Aldh1A1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Product Profile

Product Name Aldh1A1
Antibody Type Primary Antibodies
Product description 
Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during the detoxification of alcohol-derived acetaldehyde; metabolism of corticosteroids, biogenic amines and neurotransmitters; and lipid peroxidation. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1), aldehyde dehydrogenase family 1 member A1, aldehyde dehydrogenase cytosolic, ALDHII, ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). There are two major liver isoforms of ALDH1 that can localize to cytosolic or mitochondrial space. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH1A3 (ALDH6, RALDH3, ALDH1A6) is a 37 kb gene that consists of 13 exons and produces a major transcript of approximately 3.5 kb most abundant in salivary gland, stomach and kidney. ALDH3A1 (stomach type, ALDH3, ALDHIII) forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde substrates. ALDH genes upregulate as a part of the oxidative stress response, and appear to be abundant in certain tumors that have an accelerated metabolism toward chemotherapy agents.
Immunogen 
Peptide

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBICCIHCFC
WB:1:500-1:1000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:200
Species Reactivity

HumanMouseRat
Concentration 1 mg/mL.

Target Information

Alternative Names
Acetaldehyde dehydrogenase 1 antibody AHD2 antibody AL1A1_HUMAN antibody ALDC antibody Aldehyde dehydrogenase 1 family member A1 antibody Aldehyde dehydrogenase 1 soluble antibody Aldehyde dehydrogenase 1A1 antibody Aldehyde dehydrogenase antibody Aldehyde dehydrogenase cytosolic antibody Aldehyde dehydrogenase family 1 member A1 antibody Aldehyde dehydrogenase liver cytosolic antibody ALDH 1 antibody ALDH 1A1 antibody ALDH class 1 antibody ALDH
liver cytosolic antibody ALDH-E1 antibody ALDH1 A1 antibody ALDH1 antibody ALDH11 antibody ALDH1A1 antibody ALHDII antibody cytosolic antibody epididymis luminal protein 12 antibody epididymis luminal protein 9 antibody epididymis secretory sperm binding protein Li 53e antibody HEL-S-53e antibody MGC2318 antibody PUMB1 antibody RALDH 1 antibody RalDH1 antibody Retinal dehydrogenase 1 antibody
Molecular Weight(MW)

55 kDa

Cellular Localization Cytoplasm.

Database Links

SwissProt ID P00352
P24549
P51647

Application

  • Application

    Fig1: Western blot analysis of Aldh1A1 on 2 liver (1) and 2 kidney (2) tissue lysates using anti-Aldh1A1 antibody at 1/1,000 dilution.

  • Application

    Fig2: ICC staining Aldh1A1 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Application

    Fig3: ICC staining Aldh1A1 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Application

    Fig4: ICC staining Aldh1A1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

  • Application

    Fig5: Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-Aldh1A1 antibody. Counter stained with hematoxylin.

  • Application

    Fig6: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Aldh1A1 antibody. Counter stained with hematoxylin.

  • Application

    Fig7: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Aldh1A1 antibody. Counter stained with hematoxylin.

  • Application

    Fig8: Immunohistochemical analysis of paraffin-embedded 2 colon tissue using anti-Aldh1A1 antibody. Counter stained with hematoxylin.

  • Application

    Fig9: Flow cytometric analysis of A549 cells with Aldh1A1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody;black).

  • Application

    Fig10: Flow cytometric analysis of HepG2 cells with Aldh1A1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).

Positive Control 2 liver tissue lysate, 2 kidney tissue lysate, 293T, A431, HepG2, human liver tissue, human lung tissue, human kidney tissue, 2 colon tissue, A549.
Application Notes
WB:1:500-1:1000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:200

Additional Information

Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM638959
  • Price: $336.00
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  • Store: Out of stock
  • Lead time: 4~6 Week

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