Bcl-x

Catalog Number：OM638971

  • Fig1: Western blot analysis of K562 cell lysate using anti-Bcl-x.

  • Fig2： Immunohistochemical analysis of human paraffin-embedded prostate carcinoma tissue using anti-Bcl-x.

Product Profile

Product Name Bcl-x
Antibody Type Primary Antibodies
Product description 
Bcl-x, a member of the Bcl-2 protein family, inhibits cell death, or apoptosis (1). Bcl-x is expressed as two isomeric forms, Bcl-xL and Bcl-xS, and is typically present in the cytosol in association with the mitochondrial membrane. Bcl-xL forms heterodimers with various proteins, including Bax, Bak and Bcl-2 (2). It has been found that heterodimerization with Bax does not seem to be required for anti-apoptotic activity (3). Since Bcl-xL can form an ion channel in synthetic lipid membranes, there is a strong possibility that this property plays a role in heterodimerization-independent cell survival (4). The Bcl-X(S) isoform promotes apoptosis.
Immunogen 
peptide

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBICCIHCFCIP
WB:1:500-1,000
ICC:1:100
IHC:1:50-100
IP:1:10
FC:1:50
Species Reactivity

HumanMouseRat
Concentration 1 mg/mL.

Target Information

Alternative Names
Apoptosis regulator Bcl X antibody Bcl 2 like 1 antibody Bcl 2 like 1 protein antibody Bcl xL antibody BCL XL/S antibody Bcl xS antibody Bcl2 like1 antibody BCL2-related gene antibody BCL2-related protein
long isoform
included
BCLXL
included antibody BCL2-related protein
short isoform
included
BCLXS
included antibody BCL2L antibody BCL2L1 antibody Bclx antibody DKFZp781P2092 antibody MGC113803 antibody MGC99998 antibody
Molecular Weight(MW) 26 (Bcl-xL) / 19 (Bcl-xS)
Cellular Localization Cytoplasm, Nucleus membrane, Cytoplasmic vesicle Mitochondrion matrix, Mitochondrion outer/ inner membrane

Database Links

SwissProt ID Q07817

Application

  • Application

    Fig1: Western blot analysis of K562 cell lysate using anti-Bcl-x.

  • Application

    Fig2： Immunohistochemical analysis of human paraffin-embedded prostate carcinoma tissue using anti-Bcl-x.

Positive Control K562, human paraffin-embedded prostate carcinoma tissue.
Application Notes
WB:1:500-1,000
ICC:1:100
IHC:1:50-100
IP:1:10
FC:1:50

Additional Information

Form Liquid
Storage Instructions Store at -20 ℃. Stable for 12 months from date of receipt
Storage Buffer 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM638971
  • Price: $336.00
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  • Store: Out of stock
  • Lead time: 4~6 Week

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