All products Antibodies CBX4 Antibody

CBX4 Antibody

Catalog Number：OM273631

  • Immunohistochemistry staining of CBX4 in colon tissue using CBX4 Antibody.

Product Profile

Product Name CBX4 Antibody
Antibody Type Primary Antibodies
Product description 
PC2 is the human homolog of the Drosophila 'Polycomb' (Pc) protein which has been identified as a gene family member associated with a cellular memory system that is responsible for the inheritance of gene activity by progeny cells. The human Pc homolog gene is more closely related to a Xenopus Pc homolog, XPc, than to a previously described human Pc homolog, CBX2 (hPc1). However, the hPc2 and CBX2/hPc1 proteins are shown to colocalize in interphase nuclei of human U-2 OS osteosarcoma cells, suggesting that the proteins are part of a common protein complex. The human protein is believed to function as a repressor of proto-oncogene activity and that interference with hPc2 function can lead to derepression of proto-oncogene transcription and subsequently to cellular transformation. Other reports describe PC2 as a protein that has SUMO E3 activity for the corepressors CtBP and CtBP2.
Immunogen 
CBX4 antibody was raised against amino acids 95 - 107 of CBX4 (Human).

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

ELISAIFIHCWB
CBX4 antibody can be used in Western Blot, and immunohistochemistry starting at 20 μg/mL.:
Species Reactivity

Human
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol CBX4
Alternative Names
CBX4
Chromobox homolog 4
Chromobox protein homolog 4
E3 SUMO-protein ligase CBX4
NBP16
NS5ATP1-binding protein 16
HPC2
Polycomb 2 homolog
PC2
Pc class 2 homolog

Database Links

Entrez Gene 8535
Protein Accession O00257

Application

  • Application

    Immunohistochemistry staining of CBX4 in colon tissue using CBX4 Antibody.

Application Notes
CBX4 antibody can be used in Western Blot, and immunohistochemistry starting at 20 μg/mL.:

Additional Information

Form Liquid
Storage Instructions Store CBX4 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Storage Buffer 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM273631
  • Price: $336.00
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  • Lead time: 4~6 Week

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