All products Antibodies IA-1 Antibody

IA-1 Antibody

Catalog Number：OM281547

  • Western blot analysis of IA-1 in rat thymus tissue lysate with IA-1 antibody at 1 μg/mL.

Product Profile

Product Name IA-1 Antibody
Antibody Type Primary Antibodies
Product description 
IA-1 Antibody: IA-1, also known as INSM1, is an essential five zinc-finger transcription factor that while initially identified from an insulinoma cDNA library, is expressed in the developing nervous system. Specifically, IA-1 is expressed as early as E9.5 in mice in the fore-, mid- and hindbrain, spinal cord, retina, and olfactory bulb. It is thought that IA-1 functions as a transcriptional repressor, and is a part of several signaling pathways including those of Notch and sonic hedgehog in addition to that of Ngn3 during pancreatic endocrine cell differentiation. IA-1 is also expressed in multiple tumors, including the majority of neuroendocrine tumors tested so far as well as nearly 100% of all small cell lung carcinomas, indicating that IA-1 may be an important target in cancer therapy.1) Lan MS, Li Q, Lu J, et al. Genomic organization, 5’-upstream sequence, and chromosomal localization of an insulinoma-associated intronless gene, IA-1. J. Biol. Chem.1994; 269:14170-4.
Immunogen 
IA-1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human IA-1. The immunogen is located within amino acids 90 - 140 of IA-1.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAWB
IA-1 antibody can be used for detection of IA-1 by Western blot at 1 μg/mL.:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol INSM1
Alternative Names
IA-1 Antibody: IA1
IA-1
IA1
Insulinoma-associated protein 1
Zinc finger protein IA-1
Sequence Similarities Predicted species reactivity based on immunogen sequence: Bovine: (100%)

Database Links

Entrez Gene 3642
Protein Accession NP_002187

Application

  • Application

    Western blot analysis of IA-1 in rat thymus tissue lysate with IA-1 antibody at 1 μg/mL.

Positive Control 1) Cat. No. 1471 - Rat Thymus Tissue Lysate
Application Notes
IA-1 antibody can be used for detection of IA-1 by Western blot at 1 μg/mL.:

Additional Information

Form Liquid
Storage Instructions IA-1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer IA-1 Antibody is supplied in PBS containing 0.02% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

Submit an review for OM281547
Submit an review for OM281547
  • Catalog Number: OM281547
  • Price: $336.00
  • Discount Price
  • Size:
  • Store: Out of stock
  • Lead time: 4~6 Week

  • Quantity:
    - +
  • Shipping to (Please select)
Add to cart
Add to Wishlist
Search the catalog number from any major antibody supplier/brand in the search bar above. The search engine will return OmnimAbs products for these targets.
PRODUCT CATEGORIES
Primary antibodies Secondary antibodies Tags antibodies Flow cytometry antibodies
SUPPORT
Catalogs Newsletter Order Online Buying FAQs Distributor
COMPANY
Profile Strategy Careers
CONTACT
Contact us

2013 © Omnimabs , All Rights Reserved.