IA-6 Antibody: IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription.1) Ota T, Suzuki Y, Nishikawa T, et al. Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet.2004; 36:40-5.
Immunogen
IA-6 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human IA-6. The immunogen is located within amino acids 340 - 390 of IA-6.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
IA-6 antibody can be used for detection of IA-6 by Western blot at 1 - 2 μg/mL.:
Western blot analysis of IA-6 in rat thymus tissue lysate with IA-6 antibody at (A) 1 and (B) 2 μg/mL.
Positive Control
1) Cat. No. 1471 - Rat Thymus Tissue Lysate
Application Notes
IA-6 antibody can be used for detection of IA-6 by Western blot at 1 - 2 μg/mL.:
Additional Information
Form
Liquid
Storage Instructions
IA-6 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer
IA-6 Antibody is supplied in PBS containing 0.02% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
Search the catalog number from any major antibody supplier/brand in the search bar above. The search engine will return OmnimAbs products for these targets.