MYCN Antibody

Product Profile

Product Name	MYCN Antibody
Antibody Type	Primary Antibodies
Product description	MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. It is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas1) Hansford, L.M., et al., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (34), 12664-12669.
Immunogen	Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MYCN.

Key Feature

Clonality	Polyclonal
Host Species	Rabbit
Tested Applications	ELISAWB
	MYCN antibody can be used for detection of MYCN by ELISA at 1:312500. MYCN antibody can be used for detection of MYCN by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity	DogHuman
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	MYCN
Alternative Names	MYCN NMYC ODED MODED N-myc MYCNOT bHLHe37
Molecular Weight(MW)	50 kDa

Database Links

Entrez Gene	4613
Protein Accession	NP_005369

Application

Positive Control	1) Cat. No. XBL-10407 - Fetal Heart Tissue Lysate
Application Notes	MYCN antibody can be used for detection of MYCN by ELISA at 1:312500. MYCN antibody can be used for detection of MYCN by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:

Additional Information

Form	Liquid
Storage Instructions	For short periods of storage (days) store at 4˚C. For longer periods of storage, store MYCN antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer	IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt

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• Data sheet for OM285619