All products Antibodies NFE2L2-Y576 Antibody

NFE2L2-Y576 Antibody

Catalog Number：OM215278

  • Western blot analysis of Phospho-NFE2L2-Y576 in Jurkat cell line lysates (35ug/lane). NFE2L2 (arrow) was detected using the purified Pab.

  • Formalin-fixed and paraffin-embedded human lung carcinoma reacted with NFE2L2-Y576 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

  • NFE2L2-Y576 Antibody flow cytometric analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Profile

Product Name NFE2L2-Y576 Antibody
Antibody Type Primary Antibodies

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

WBIHCFC
WB~~1:100~500 IHC~~1:50~100 FC~~1:10~50:
Species Reactivity

Human
Concentration 1 mg/ml
Purification

Target Information

Gene Synonyms
NRF2
Alternative Names
NFE2L2
NRF2
Nuclear factor erythroid 2-related factor 2
HEBP1
Nuclear factor
erythroid derived 2
like 2
Molecular Weight(MW) 67827 Da
Function
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region
Tissue Specificity Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle
Cellular Localization Cytoplasm, cytosol. Nucleus. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents

Database Links

Entrez Gene 4780
Nucleotide Accession NP_006155

Application

  • Application

    Western blot analysis of Phospho-NFE2L2-Y576 in Jurkat cell line lysates (35ug/lane). NFE2L2 (arrow) was detected using the purified Pab.

  • Application

    Formalin-fixed and paraffin-embedded human lung carcinoma reacted with NFE2L2-Y576 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

  • Application

    NFE2L2-Y576 Antibody flow cytometric analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Application Notes
WB~~1:100~500 IHC~~1:50~100 FC~~1:10~50:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM215278
  • Price: $336.00
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  • Lead time: 2~3 Week

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