NFKBIL1 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the NFKBIL1 antibody detected the NFKBIL1 protein (arrow).
NFKBIL1 Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Confocal immunofluorescent analysis of NFKBIL1 Antibody (Center)(Cat#AP10682c) with MDA-MB435 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
Product Name | NFKBIL1 Antibody (Center) |
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Antibody Type | Primary Antibodies |
Clonality | Polyclonal |
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Isotype | Ig |
Host Species | Rabbit |
Tested Applications | |
WB~~1:100~500 FC~~1:10~50 IF~~1:10~50: |
|
Species Reactivity | |
Concentration | 1 mg/ml |
Purification |
Gene Synonyms | IKBL |
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Alternative Names | NFKBIL1 IKBL NF-kappa-B inhibitor-like protein 1 Inhibitor of kappa B-like protein Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
Molecular Weight(MW) | 43204 Da |
Function | Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon- regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli |
Tissue Specificity | Detected in different cell types including monocytes, T-cells, B-cells and hepatocytes |
Cellular Localization | Nucleus. Note=Nuclear localization with a speckled expression pattern in some cells. Colocalizes with CACTIN in the nucleus |
Entrez Gene | 4795 |
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Nucleotide Accession | NP_001138434.1 |
NFKBIL1 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the NFKBIL1 antibody detected the NFKBIL1 protein (arrow).
NFKBIL1 Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Confocal immunofluorescent analysis of NFKBIL1 Antibody (Center)(Cat#AP10682c) with MDA-MB435 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
Application Notes | WB~~1:100~500 FC~~1:10~50 IF~~1:10~50: |
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Form | Liquid |
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Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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