All products Antibodies NKX2-2 Antibody

NKX2-2 Antibody

Catalog Number：OM286253

  • Immunohistochemistry of NKX2-2 in human kidney tissue with NKX2-2 antibody at 2.5 μg/mL.

  • Western blot analysis of NKX2-2 in rat kidney tissue lysate with NKX2-2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

  • Immunofluorescence of NKX2-2 in human kidney tissue with NKX2-2 antibody at 20 μg/mL.

Product Profile

Product Name NKX2-2 Antibody
Antibody Type Primary Antibodies
Product description 
NKX2-2 Antibody: NKX2-2 (NK2 homeobox 2) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-2 is crucial in the development of pancreatic islet cell differentiation and activates the ghrelin-promoter in these cells. NKX2-2 is expressed at the onset of pancreatic epithelium formation and becomes restricted to mature α-, β- and PP cells, and in NKX2-2-null mice embryos, all β-cells and most a-cells are replaced by ghrelin-positive cells. NKX2-2 is also thought to be involved in ventral neuronal patterning and floor plate development and commissural axon guidance.1) Sussel L, Kalamaras J, Hartigan-O’Connor DJ, et al. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Development 1998; 125:2213-21
Immunogen 
NKX2-2 antibody was raised against a 19 amino acid synthetic peptide near the center of human NKX2-2. The immunogen is located within amino acids 90 - 140 of NKX2-2.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAIFIHC-PWB
NKX2-2 antibody can be used for detection of NKX2-2 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol NKX2-2
Alternative Names
NKX2-2 Antibody: NKX2B
NKX2.2
NKX2B
Homeobox protein NK-2 homolog B
Sequence Similarities 2) Cat. No. 10-401 - Human Kidney Tissue Slide
Tissue Specificity NKX2-2 antibody is predicted to not cross-react with other NK2 homeobox family members.

Database Links

Entrez Gene 4821
Protein Accession NP_002500

Application

  • Application

    Immunohistochemistry of NKX2-2 in human kidney tissue with NKX2-2 antibody at 2.5 μg/mL.

  • Application

    Western blot analysis of NKX2-2 in rat kidney tissue lysate with NKX2-2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

  • Application

    Immunofluorescence of NKX2-2 in human kidney tissue with NKX2-2 antibody at 20 μg/mL.

Positive Control 1) Cat. No. 1465 - Rat Kidney Tissue Lysate
Application Notes
NKX2-2 antibody can be used for detection of NKX2-2 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.:

Additional Information

Form Liquid
Storage Instructions NKX2-2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer NKX2-2 Antibody is supplied in PBS containing 0.02% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

Submit an review for OM286253
Submit an review for OM286253
  • Catalog Number: OM286253
  • Price: $336.00
  • Discount Price
  • Size:
  • Store: Out of stock
  • Lead time: 4~6 Week

  • Quantity:
    - +
  • Shipping to (Please select)
Add to cart
Add to Wishlist
Search the catalog number from any major antibody supplier/brand in the search bar above. The search engine will return OmnimAbs products for these targets.
PRODUCT CATEGORIES
Primary antibodies Secondary antibodies Tags antibodies Flow cytometry antibodies
SUPPORT
Catalogs Newsletter Order Online Buying FAQs Distributor
COMPANY
Profile Strategy Careers
CONTACT
Contact us

2013 © Omnimabs , All Rights Reserved.