All products Antibodies Nephrin (Y1210) antibody

Nephrin (Y1210) antibody

Catalog Number：OM215202

  • Nephrin (Y1210) antibody western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the Nephrin antibody detected the Nephrin protein (arrow).

  • Nephrin (Y1210) antibody western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Nephrin antibody detected the Nephrin protein (arrow).

  • Nephrin Antibody (Y1210) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Profile

Product Name Nephrin (Y1210) antibody
Antibody Type Primary Antibodies

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

WBFC
WB~~1:100~500 FC~~1:10~50:
Species Reactivity

Human
Concentration 1 mg/ml
Purification

Target Information

Gene Synonyms
NPHN
Alternative Names
NPHS1
NPHN
Nephrin
Renal glomerulus-specific cell adhesion receptor
Molecular Weight(MW) 134742 Da
Function
Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion (By similarity)
Tissue Specificity Specifically expressed in podocytes of kidney glomeruli
Cellular Localization Cell membrane; Single-pass type I membrane protein (Potential). Note=Predominantly located at podocyte slit diaphragm between podocyte foot processes. Also associated with podocyte apical plasma membrane

Database Links

Entrez Gene 4868
Nucleotide Accession NP_004637.1

Application

  • Application

    Nephrin (Y1210) antibody western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the Nephrin antibody detected the Nephrin protein (arrow).

  • Application

    Nephrin (Y1210) antibody western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Nephrin antibody detected the Nephrin protein (arrow).

  • Application

    Nephrin Antibody (Y1210) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Application Notes
WB~~1:100~500 FC~~1:10~50:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM215202
  • Price: $336.00
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  • Lead time: 2~3 Week

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