PDK1 (phospho Ser241) Antibody

Product Profile

Product Name	PDK1 (phospho Ser241) Antibody
Antibody Type	Primary Antibodies
Product description	Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-ζ, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development.1) Scheid MP, et al. (2005) Mol Cell Biol; 25 (6): 2347-63Chen H, et al. (2001) Biochemistry; 40 (39): 11851-9Sato S, et al. (2002) J Biol Chem; 277 (42): 39360-7Lim MA, et al. (2003) Proc Natl Acad Sci U S A; 100 (24): 14006-11
Immunogen	PDK1 (Phospho-Ser241) antibody was raised against a peptide sequence around phosphorylation site of serine 241 (A-N-S (p) -F-V) derived from Human PDK1.

Key Feature

Clonality	Polyclonal
Host Species	Rabbit
Tested Applications	IFIHCWB
	Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200:
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml
Purification	Affinity purified

Target Information

Gene Symbol	PDPK1
Alternative Names	PDK1 PDPK2 PRO0461 NFKB3 PDPK1 PkB kinase Protein kinase B kinase hPDK1 kinase PDK1
Molecular Weight(MW)	63 kDa
Tissue Specificity	This antibody detects endogenous level of PDK1 only when phosphorylated at serine 241.

Database Links

Entrez Gene	5170
Protein Accession	NP_002604.1

Application

Application Notes	Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200:

Additional Information

Form	Liquid
Storage Instructions	Store antibody at -20˚C for up to one year.
Storage Buffer	Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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• Data sheet for OM287742