All products Antibodies Rabbit anti-TANK polyclonal antibody - N-terminal region

Rabbit anti-TANK polyclonal antibody - N-terminal region

Catalog Number：OM108729

Product Profile

Product Name Rabbit anti-TANK polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Immunogen 
The immunogen for anti-TANK antibody: synthetic peptide directed towards the N terminal of human TANK

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

BovineGuinea PigHorseHumanMousePigRabbitRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol TANK
Gene Synonyms
I-TRAF
TRAF2
Gene Full Name TRAF family member-associated NFKB activator
Gene Summary
The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, TANK can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation.The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Two transcript variants encoding different isoforms have been found for this gene.
Alternative Names
I-TRAF
TRAF2
Molecular Weight(MW) 48kDa
Sequence 425 amino acids

Database Links

Entrez Gene 10010
SwissProt ID Q92844
Protein Accession NP_004171

Application

Application Notes
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

Submit an review for OM108729
Submit an review for OM108729
  • Catalog Number: OM108729
  • Price: $336.00
  • Discount Price
  • Size:
  • Store: In stock
  • Lead time: 2~3 Week

  • Quantity:
    - +
  • Shipping to (Please select)
Add to cart
Add to Wishlist
Search the catalog number from any major antibody supplier/brand in the search bar above. The search engine will return OmnimAbs products for these targets.
PRODUCT CATEGORIES
Primary antibodies Secondary antibodies Tags antibodies Flow cytometry antibodies
SUPPORT
Catalogs Newsletter Order Online Buying FAQs Distributor
COMPANY
Profile Strategy Careers
CONTACT
Contact us

2013 © Omnimabs , All Rights Reserved.