All products Antibodies TRAF6 Antibody

TRAF6 Antibody

Catalog Number：OM293887

  • Western blot analysis of TRAF6 in PC-3 cell lysates with TRAF6 antibody at 1 μg/mL in the presence (A) or absence (B) of 1 μg blocking peptide.

  • Immunofluorescence of TRAF6 in K562 cells with TRAF6 antibody at 20 μg/mL.

  • Immunocytochemistry of TRAF6 in K562 cells with TRAF6 antibody at 0.5 μg/mL.

Product Profile

Product Name TRAF6 Antibody
Antibody Type Primary Antibodies
Product description 
TRAF6 Antibody: Signals from the IL-1 receptor (IL-1R)/Toll-like receptor (TLR) and TNF receptor (TNFR) superfamilies are critical for regulating the function of antigen-presenting cells. Signals transduced by these molecules lead to increased expression and activation of transcription factors such as NF-κB. TNF receptor-associated factor 6 (TRAF6) is unique in that it is a signaling adapter molecule common to both families. TRAF6 is important in cytokine production, dendritic cell (DC) maturation, and the T cell stimulatory capacity of DCs in response to TLR and CD40 ligands. It can be activated in the IL-1R/TLR signaling pathway by IL-1 receptor-associated kinase 1 (IRAK-1) or by other TLR adaptor molecules such as TRIF. Also, it has been shown that TRAF6 can interact directly with TNFR family members CD40 and RANK.1) Takeda K, Kaisho T, and Akira S. Toll-like receptors. Annu. Rev. Immunol. 2003; 21:335-76.
Immunogen 
TRAF6 antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human TRAF6. The immunogen is located within the last 50 amino acids of TRAF6.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAICCIFWB
TRAF6 antibody can be used for detection of TRAF6 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.:
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol TRAF6
Alternative Names
TRAF6 Antibody: RNF85
MGC:3310
RNF85
E3 ubiquitin-protein ligase TRAF6
Sequence Similarities 3) Cat. No. 17-004 - K-562 Cell Slide

Database Links

Entrez Gene 7189
Protein Accession NP_004611

Application

  • Application

    Western blot analysis of TRAF6 in PC-3 cell lysates with TRAF6 antibody at 1 μg/mL in the presence (A) or absence (B) of 1 μg blocking peptide.

  • Application

    Immunofluorescence of TRAF6 in K562 cells with TRAF6 antibody at 20 μg/mL.

  • Application

    Immunocytochemistry of TRAF6 in K562 cells with TRAF6 antibody at 0.5 μg/mL.

Positive Control 1) Cat. No. 1216 - PC-3 Cell Lysate
Application Notes
TRAF6 antibody can be used for detection of TRAF6 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.:

Additional Information

Form Liquid
Storage Instructions TRAF6 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer TRAF6 Antibody is supplied in PBS containing 0.02% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM293887
  • Price: $336.00
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