All products Antibodies TRIM23 Antibody

TRIM23 Antibody

Catalog Number：OM294020

  • TRIM23 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

  • Western blot analysis in HL-60 cell line lysates (35ug/lane).

Product Profile

Product Name TRIM23 Antibody
Antibody Type Primary Antibodies
Product description 
The protein encoded by this gene is a member of the
tripartite motif (TRIM) family. The TRIM motif includes three
zinc-binding domains, a RING, a B-box type 1 and a B-box type 2,
and a coiled-coil region. This protein is also a member of the ADP
ribosylation factor family of guanine nucleotide-binding family of
proteins. Its carboxy terminus contains an ADP-ribosylation factor
domain and a guanine nucleotide binding site, while the amino
terminus contains a GTPase activating protein domain which acts on
the guanine nucleotide binding site. The protein localizes to
lysosomes and the Golgi apparatus. It plays a role in the formation
of intracellular transport vesicles, their movement from one
compartment to another, and phopholipase D activation. Three
alternatively spliced transcript variants for this gene have been
described.1) Arimoto, K., et al. Proc. Natl. Acad. Sci. U.S.A. 107(36):15856-15861(2010)
Immunogen 
This TRIM23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the N-terminal region of human TRIM23.

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
Species Reactivity

Human
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol TRIM23
Alternative Names
E3 ubiquitin-protein ligase TRIM23
632-
ADP-ribosylation factor domain-containing protein 1
GTP-binding protein ARD-1
RING finger protein 46
Tripartite motif-containing protein 23
TRIM23
ARD1
ARFD1
RNF46
Molecular Weight(MW) 64 kDa
Sequence Similarities Predicted species reactivity based on immunogen sequence: Mouse

Database Links

Entrez Gene 373
Protein Accession P36406

Application

  • Application

    TRIM23 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

  • Application

    Western blot analysis in HL-60 cell line lysates (35ug/lane).

Application Notes
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:

Additional Information

Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM294020
  • Price: $336.00
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