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Rabbit anti-NFIL3 polyclonal antibody - middle region

Catalog Number:OM105274
OM105274
Discount Price
OM105274-100ul
1~2 Week
100ul
OM105274-50ul
50ul
OM105274-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-NFIL3 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias E4BP4, IL3BP1, NF-IL3A, NFIL3A
Immunogen The immunogen for anti-NFIL3 antibody: synthetic peptide directed towards the middle region of human NFIL3
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineHorseHumanMousePigRabbitRatSheepZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol NFIL3
Gene Synonyms E4BP4
IL3BP1
NF-IL3A
NFIL3A
Gene Full Name Nuclear factor, interleukin 3 regulated
Gene Summary NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
Alternative Names E4BP4
IL3BP1
NF-IL3A
NFIL3A
Molecular Weight(MW) 51kDa
Sequence 462 amino acids
Database Links
Entrez Gene 4783
SwissProt ID Q16649
Protein Accession NP_005375
Application

Western blot

Host: Rabbit Target Name: NFIL3 Sample Tissue: Human Fetal Brain Antibody Dilution: 1.0ug/ml

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human brain
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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