Western blot
1.25ug/ml| Product Name | NFIL3 antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-NFIL3 antibody: synthetic peptide directed towards the N terminal of human NFIL3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | Bovine,Human,Pig,Sheep |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | NFIL3 |
|---|---|
| Gene Synonyms | E4BP4 IL3BP1 NFIL3A NF-IL3A |
| Gene Full Name | Nuclear factor, interleukin 3 regulated |
| Gene Summary | NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia. |
| Alternative Names | E4BP4 IL3BP1 NFIL3A NF-IL3A |
| Molecular Weight(MW) | 51kDa |
| Sequence | 462 amino acids |
Western blot
1.25ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
