Immunohistochemical
Western blot
1.25ug/ml| Product Name | POU4F3 antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-POU4F3 antibody: synthetic peptide directed towards the middle region of human POU4F3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB,IHC |
| Species Reactivity | Bovine,Dog,Guinea Pig,Pig,Rabbit,Rat,Zebra Fish |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | POU4F3 |
|---|---|
| Gene Synonyms | BRN3C DFNA15 |
| Gene Full Name | POU class 4 homeobox 3 |
| Gene Summary | POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members. |
| Alternative Names | BRN3C DFNA15 |
| Molecular Weight(MW) | 37kDa |
| Sequence | 338 amino acids |
Immunohistochemical
Western blot
1.25ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
