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Rabbit anti-KEAP1 polyclonal antibody - N-terminal region
Catalog Number:OM107033
OM107033
Discount Price
OM107033-100ul
1~2 Week
100ul
OM107033-50ul
50ul
OM107033-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-KEAP1 polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias INrf2, KLHL19
Immunogen The immunogen for anti-KEAP1 antibody: synthetic peptide directed towards the N terminal of human KEAP1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHorseHumanMousePigRatZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol KEAP1
Gene Synonyms INrf2
KLHL19
Gene Full Name Kelch-like ECH-associated protein 1
Gene Summary KEAP1 contains KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Alternative Names INrf2
KLHL19
Molecular Weight(MW) 70kDa
Sequence 624 amino acids
Database Links
Entrez Gene 9817
SwissProt ID Q14145
Protein Accession NP_987096
Application

Immunohistochemical

Kidney

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Transfected 293T
Application Notes WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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