Western blot
AGTR1 antibody - N-terminal region validated by WB using Mouse Brain Membranes at 1:4000.Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human heart| Product Name | Rabbit anti-AGTR1 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R, AT1R |
| Immunogen | The immunogen for anti-AGTR1 antibody: synthetic peptide directed towards the N terminal of human AGTR1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
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| Species Reactivity | BovineDogGuinea PigHumanMousePigRabbitSheep |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | AGTR1 |
|---|---|
| Gene Synonyms | AG2S AGTR1A AGTR1B AT1 AT1B AT2R1 AT2R1A AT2R1B HAT1R AT1R |
| Gene Full Name | Angiotensin II receptor, type 1 |
| Gene Summary | Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. AGTR1 is the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. AGTR1 may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans.Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. |
| Alternative Names | AG2S AGTR1A AGTR1B AT1 AT1B AT2R1 AT2R1A AT2R1B HAT1R AT1R |
| Molecular Weight(MW) | 41kDa |
| Sequence | 359 amino acids |
Western blot
AGTR1 antibody - N-terminal region validated by WB using Mouse Brain Membranes at 1:4000.
Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human heart| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
