Application
Immunohistochemistry of AGTR1 in mouse kidney tissue with AGTR1 antibody at 2.5 μg/ml.Application
Immunohistochemistry of AGTR1 in mouse kidney tissue with AGTR1 antibody at 2.5 μg/mL.Application
Immunofluorescence of AGTR1 in Mouse Kidney cells with AGTR1 antibody at 20 μg/mL.| Product Name | AGTR1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AGTR1 Antibody: AT1, AG2S, AT1B, AT1R, AT1AR, AT1BR, AT2R1, HAT1R, AGTR1B, AGTR1A, AT2R1B, Type-1 angiotensin II receptor, AT1 |
| Product description | AGTR1 Antibody: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. AGTR1, the type 1 receptor, is thought to mediate the major cardiovascular effects of angiotensin II and may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. AGTR1 has recently been found to regulate the differentiation of bone marrow-derived monocyte lineage progenitors from hematopoietic stem cells, indicating the diversity of the roles of AGTR1.1) Mottl AK, Shoham DA, and North KE. Angiotensin II type 1 receptor polymorphisms and susceptibility to hypertension: A HuGE review. Gen. in Med.2008; 10:560-574. |
| Immunogen | AGTR1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human AGTR1. The immunogen is located within amino acids 210 - 260 of AGTR1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| AGTR1 antibody can be used for detection of AGTR1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | AGTR1 |
|---|---|
| Alternative Names | AGTR1 Antibody: AT1 AG2S AT1B AT1R AT1AR AT1BR AT2R1 HAT1R AGTR1B AGTR1A AT2R1B Type-1 angiotensin II receptor AT1 |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Pig: (100%) |
Application
Immunohistochemistry of AGTR1 in mouse kidney tissue with AGTR1 antibody at 2.5 μg/ml.
Application
Immunohistochemistry of AGTR1 in mouse kidney tissue with AGTR1 antibody at 2.5 μg/mL.
Application
Immunofluorescence of AGTR1 in Mouse Kidney cells with AGTR1 antibody at 20 μg/mL.| Positive Control | 1) Cat. No. 1405 - Mouse Kidney Tissue Lysate |
|---|---|
| Application Notes | AGTR1 antibody can be used for detection of AGTR1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | AGTR1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | AGTR1 Antibody is supplied in PBS containing 0.02% sodium azide. |
