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Rabbit anti-DTL polyclonal antibody - N-terminal region

Catalog Number:OM112455
OM112455
Discount Price
OM112455-100ul
1~2 Week
100ul
OM112455-50ul
50ul
OM112455-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-DTL polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias CDT2, DCAF2, L2DTL, RAMP
Immunogen The immunogen for anti-DTL antibody: synthetic peptide directed towards the N terminal of human DTL
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity DogGuinea PigHorseHumanMousePigRabbitRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol DTL
Gene Synonyms CDT2
DCAF2
L2DTL
RAMP
Gene Full Name Denticleless E3 ubiquitin protein ligase homolog (Drosophila)
Gene Summary DTL is required for CDT1 proteolysis in response to DNA damage through the CUL4-DDB1 E3 ubiquitin-protein ligase. It seems to be necessary to ensure proper cell cycle regulation of DNA replication. DTL may function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. It also may play a role in cell proliferation of NT2 embryonal carcinoma cells.
Alternative Names CDT2
DCAF2
L2DTL
RAMP
Molecular Weight(MW) 79kDa
Sequence 730 amino acids
Database Links
Entrez Gene 51514
SwissProt ID Q9NZJ0
Protein Accession NP_057532
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 721_B cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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