Immunofluorescence
LiveWestern blot
0.2-1 ug/ml| Product Name | MAP4K4 antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-MAP4K4 antibody: synthetic peptide directed towards the N terminal of human MAP4K4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB,IHC |
| Species Reactivity | Bovine,Dog,Guinea Pig,Horse,Human,Mouse,Rabbit,Rat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MAP4K4 |
|---|---|
| Gene Synonyms | FLH21957 FLJ10410 FLJ20373 FLJ90111 HGK KIAA0687 NIK MEKKK4 |
| Gene Full Name | Mitogen-activated protein kinase kinase kinase kinase 4 |
| Gene Summary | MAP4K4 is the serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. MAP4K4 appears to act upstream of the JUN N-terminal pathway.The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Alternative Names | FLH21957 FLJ10410 FLJ20373 FLJ90111 HGK KIAA0687 NIK MEKKK4 |
| Molecular Weight(MW) | 133kDa |
| Sequence | 1166 amino acids |
Immunofluorescence
Live
Western blot
0.2-1 ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
