Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: A549 cell lysate| Product Name | Rabbit anti-PACS2 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FLJ25488, KIAA0602, PACS1L, PACS-2 |
| Immunogen | The immunogen for anti-PACS2 antibody: synthetic peptide directed towards the middle region of human PACS2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineGuinea PigHorseHumanMouseRabbitZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PACS2 |
|---|---|
| Gene Synonyms | FLJ25488 KIAA0602 PACS1L PACS-2 |
| Gene Full Name | Phosphofurin acidic cluster sorting protein 2 |
| Gene Summary | PACS2 is the multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer,PACS2 translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death.PACS2 may also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments. |
| Alternative Names | FLJ25488 KIAA0602 PACS1L PACS-2 |
| Molecular Weight(MW) | 98kDa |
| Sequence | 889 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: A549 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
