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Rabbit anti-CASP4 Antibody - middle region

Catalog Number:OM117859
OM117859
Discount Price
OM117859-100ul
1~2 Week
100ul
OM117859-50ul
50ul
OM117859-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-CASP4 Antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX
Immunogen The immunogen for Anti-CASP4 antibody is: synthetic peptide directed towards the middle region of Human CASP4
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CASP4
Gene Synonyms ICE(rel)II
ICEREL-II
ICH-2
Mih1/TX
TX
Gene Full Name caspase 5, apoptosis-related cysteine peptidase
Gene Summary This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
Alternative Names ICE(rel)II
ICEREL-II
ICH-2
Mih1/TX
TX
Molecular Weight(MW) 35kDa
Sequence 321 amino acids
Database Links
Entrez Gene 837
SwissProt ID P49662-2
Protein Accession NP_150649
Application

Western blot

Host: Rabbit Target Name: CASP4 Sample Tissue: A549 Whole Cell lysates Antibody Dilution: 1.0ug/ml
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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