| Gene Symbol |
CXCR6
|
| Gene Synonyms |
BONZO CD186 STRL33 TYMSTR |
| Gene Full Name |
Chemokine (C-X-C motif) receptor 6 |
| Gene Summary |
CXCR6 is a receptor for the C-X-C chemokine CXCL16. It is used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.The CXCR6/AKT/mTOR pathway plays a central role in the development of prostate cancer. CXCR6 and CXCR3 act coordinately with respective ligands and are involved in the pathophysiology of Juvenile Idiopathic Arthritis-associated inflammatory processes. The CXCL16-CXCR6-system express in human schwannomas of different localization and in malignant peripheral nerve sheath tumors. The protein may play an important role in the retention of T cells within the lung. |
| Alternative Names |
BONZO CD186 STRL33 TYMSTR |
| Molecular Weight(MW) |
39kDa |
| Sequence |
342 amino acids |