WB
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal brain tissue, mouse brain tissue, Primary antibody: CXCR6 Antibody at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutesIHC
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CXCR6 Antibody at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)IHC
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CXCR6 Antibody at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)| Product Name | Rabbit anti-CXCR6 Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Fusion protein of Human CXCR6 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:500-1:2000 IHC:1:50-1:200 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CXCR6 |
|---|---|
| Gene Synonyms | BONZO CD186 CDw186 STRL33 TYMSTR |
| Gene Full Name | C-X-C motif chemokine receptor 6 |
| Gene Summary | The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. This gene, which maps to the chemokine receptor gene cluster, is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signalling pathway that regulates T lymphocyte migration to various peripheral tissues (the liver, spleen red pulp, intestine, lungs, and skin) and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an important first line of defense against respiratory pathogens. The encoded protein serves as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4. [provided by RefSeq, Aug 2020] |
| Alternative Names | CXCR6 BONZO STRL33 TYMSTR C-X-C chemokine receptor type 6 CXC-R6 CXCR-6 CDw186 G-protein coupled receptor STRL33 G-protein coupled receptor bonzo CD antigen CD186 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
WB
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal brain tissue, mouse brain tissue, Primary antibody: CXCR6 Antibody at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
IHC
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CXCR6 Antibody at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
IHC
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CXCR6 Antibody at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)| Application Notes | WB:1:500-1:2000 IHC:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
