Application
MCM7 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MCM7 antibody detected the MCM7 protein (arrow).| Product Name | MCM7 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MCM7; CDC47; MCM2; DNA replication licensing factor MCM7; CDC47 homolog; P1.1-MCM3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CDC47 MCM2 |
|---|---|
| Alternative Names | MCM7 CDC47 MCM2 DNA replication licensing factor MCM7 CDC47 homolog P1.1-MCM3 |
| Molecular Weight(MW) | 81308 Da |
| Function | Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage |
| Tissue Specificity | This MCM7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-142 amino acids from the N-terminal region of human MCM7. |
| Cellular Localization | Nucleus (By similarity). |
| Entrez Gene | 4176 |
|---|---|
| Nucleotide Accession | NP_877577.1 NP_005907.3 |
Application
MCM7 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MCM7 antibody detected the MCM7 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
